- Ingredient: Insulin Lispro
- Manufacturer: Eli Lilly
- Brand Name: Humalog
- Category: Diabetes
- Buy Humalog Mix 25 (Insulin Lispro) 100 IU Cartridges 3 ml
- Item price: $19.80
Humalog Mix 25 is a hypoglycemic drug, a combination of quick and medium duration insulin analogues. Humalog Mix 25 is a DNA recombinant analogue of human insulin and is a ready-made mixture consisting of lyspro insulin solution (a quick-acting analog of human insulin) and a suspension of lyspro protamine insulin (medium-duration human insulin analogue).
The main action of insulin lyspro is the regulation of glucose metabolism. In addition, it has anabolic and anti-catabolic effects on various body tissues.
In muscle tissue, there is an increase in the content of glycogen, fatty acids, glycerol, an increase in protein synthesis and an increase in the consumption of amino acids, but at the same time there is a decrease in glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism and the release of amino acids.
It was shown that lyspro insulin is equimolar to human insulin, but its action develops faster and lasts for a shorter time. The onset of the drug is after about 15 minutes, which allows it to be administered immediately before meals (0-15 minutes before meals), compared with ordinary human insulin.
After a s / c injection of Humalog Mix 25, a rapid onset of action and an early peak in lyspro insulin activity are observed. The action profile of the insulin lysproprotamine is similar to the action profile of the usual insulin isophan with a duration of approximately 15 hours.
Indications
Humalog Mix 25 Indications
Diabetes mellitus requiring insulin therapy.
Contraindications
Hypoglycemia; hypersensitivity to the components of the drug.
Dosage and administration
The doctor determines the dose individually, depending on the level of glucose in the blood. The regimen of insulin administration is individual.
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The drug should be administered sc.
In / in the introduction of the drug Humalog Mix 25 is contraindicated.
The temperature of the administered drug should be at room temperature. SC should be administered to the shoulder, thigh, buttock, or abdomen. The injection sites should be alternated so that the same place is used no more than 1 time per month.
When s / to the introduction of the drug Humalog Mix 25, care must be taken to avoid getting the drug into a blood vessel.
After the injection, the injection site should not be massaged.
When installing a cartridge in an insulin injection device and attaching a needle before insulin administration, the instructions of the manufacturer of the insulin injection device must be strictly observed.
How to take, course of administration and dosage
Subcutaneously in the shoulder, thigh, buttock or abdomen. The injection sites should be alternated so that the same place is used no more than 1 time per month. With subcutaneous administration of the drug Humalog Mix 25, care must be taken to prevent the drug from entering the blood vessel. After the injection, the injection site should not be massaged.
The temperature of the administered drug should be at room temperature.
The doctor determines the dose individually, depending on the level of glucose in the blood. The regimen of insulin administration is individual.
Intravenous administration of Humalog Mix 25 is contraindicated.
When installing a cartridge in an insulin injection device and attaching a needle before insulin administration, the instructions of the manufacturer of the insulin injection device must be strictly observed.
The rules of administration of the drug Humalog Mix 25
Preparation for the introduction. Immediately before use, the Humalog Mix 25 cartridge should be rolled between the palms 10 times and shaken, turning 180 ° also 10 times to resuspend insulin until it looks like a uniform cloudy liquid or milk. Shake vigorously, as this can lead to foam, which can interfere with the correct dose. To facilitate mixing, the cartridge contains a small glass bead. The drug should not be used if it contains flakes after mixing.